When Councilwoman Liang attempts to redevelop the downtown area, the demolition efforts disturb a man named Clancy, who has the ability to control insects. Meanwhile, as Ben stops a criminal as Upgrade, he spots at a nearby ice cream truck. When he climbs inside to get a snack, he gets himself locked inside and ends up catching a cold. The virus binds with the alien DNA in the Omnitrix, causing side effects, and weakening his normally powerful forms. On top of that, Clancy kidnaps the councilwoman and threatens the entire city with a meltdown at the nuclear power plant. Now, Ben must save the day while dealing with the strange side effects in his alien forms.